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Finally contact Readysell and have our support team turn on automatic cost and sell updates for you. We would normally set this to run each day for you. You can set it to run once a week if you have a retail area and want to print price change labels only once a week, in order to reduce the time spent replacing labels.
You should not run price book runs on a regular basis. Once you have one good price book run posted you should turn on automatic overnight updates. Then you do not have to load a catalogue or price book run ever again!!!